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Veterinary Pharmacology and Therapeutics Journal

ICCM

Kansas State University
P200 Mosier Hall
Manhattan, KS 66506

 

785-532-4977
785-532-4557 fax
iccm@k-state.edu

Mission

The focus of this institute is to apply quantitative mathematical modeling and simulation techniques to problems in animal health and welfare as well as predict their impact on human health and food safety. It will specifically focus on bridging experimental data generated in laboratory studies to their application in whole animals and populations.

Disciplines involved include pharmacometrics, pharmacokinetics, computational epidemiology, molecular modeling and other areas of biomathematics with application to animal health and disease. In contrast to groups solely focused on theoretical in silico modeling, research conducted in the ICCM will involve laboratory, in vivo and field experiments to insure optimal design of the complete experimental continuum.

A second unique aspect of this Institute's mission is its focus on veterinary species, comparative medicine and animal health; a mission greatly facilitated by its location in the international Animal Health Corridor and Kansas State University's involvement in the National Biological and Agricultural Facility (NBAF) on its Manhattan campus.

The ICCM was identified by Certara, Inc. as a Phoenix Center of Excellence, its first focused solely on animal health.

Examples of the types of research to be conducted include:

  • Design of integrated physiological based pharmacokinetic (PBPK) models specifically for veterinary species and animal health endpoints.
  • Improved determination of tissue withdrawal times of drugs in animals with disease.
  • Simulation of clinical trials to optimize design of animal drugs by reducing use of animals now employed in traditional clinical trials.
  • Temporal and geospatial analysis of environmental toxicant distributions.
  • Developing robust approaches to extrapolate results from in vitro laboratory experiments to intact animals, with a focus on epithelial transport phenomenon and improved methods for drug delivery.
  • Develop modeling approaches to predict behavior of nanomaterials in biological systems.
  • Develop and refine approaches to animal-derived data modeling for the purpose of chemical risk assessment.
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News

Cluster faculty seminars 

"Modeling Dynamics and Drivers of Antimicrobial Resistance in Animal Enteric Bacteria" by Dr. Victoriya Volkova at Read more...

 

Dr. Jim RiviereExpert Exchange
Dr. Jim Riviere


University clinical pharmacologist collaborates with international colleagues about chronic lead intoxication in goats
  Read More

KSU Faculty Cluster hire for ICCM:

Kansas State University (KSU) announces the availability of seven tenure-track assistant/associate professor positions in comparative pharmacometrics, biomathematics/biostatistics, cell biology and nanomedicine /nanobiology  Read More

ICCM Construction progressing well:
Construction on the new ICCM facilities is on schedule and progressing well. Occupation of the new state-of-the-art facilities will occur early in 2014.